Clinical Toxicology Clinical Trials
The Clinical Toxicology Clinical Trial department provides a unique combination of laboratory research with clinical research resulting in high impact research. This research provides changes and developments to clinical practices, service and guidelines.
The department’s laboratory has the ability to measure venom and antivenom levels in snake and spider bites. It is one of only a few in the world with the capability to measure venom concentrations.
Clinical Trials currently in progress include:
- SARPO (A non-inferiority randomised controlled trial of a Shorter Acetylcysteine Regimen for Paracetamol Overdose – the SARPO trial. This is a study to determine if a smaller dose of the antidote for paracetamol poisoning can be used in patients that take less than 30g in overdose (smaller overdoses)
- A randomised controlled trial of antivenom for red-bellied black snake envenoming. This is a placebo randomised controlled trial of antivenom for red-bellied black snake envenoming, investigating whether antivenom within 6 hours versus no antivenom prevents muscle damage from the toxins.